Raw Caffeic acid phenethyl ester powder (104594-70-9)

December 28, 2018
SKU: 104594-70-9
5.00 si 5 dabere na 1 ahịa fim

Raw Caffeic acid phenethyl ester ntụ ntụ bụ phenethyl alcohol ester nke caffeic acid na bioactive ...... ..


ọnọdụ: Na Production Production
Otu: 25kg / Drum
ikike: 1180kg / ọnwa

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Product Name Raw Caffeic acid phenethyl ester ntụ ntụ
Chemical Aha Raw Caffeic acid phenethyl ester ntụ ntụ;

Pentylethyl caffeate; Pentethyl caffeate; Caffeic acid 2-phenylthyl ester; β-Phenylthyl caffeate;

2-Phenylethyl (2E) -3- (3,4-dihydroxyphenyl) acrylate

Brand Name Enweghị data maka dịnụ
Klaasị ọgwụ ọjọọ Ndị na-egbochi Tyrosine Kinase, Ndị na-emechi ihe
CAS Number 104594-70-9
InChIKey SWUARLUWKZWEBQ-VQHVLOKHSA-N
molekụla Fnhazi C17H16O4
molekụla Wasatọ 284.311 g / mol
Nkịtị Monoisotopic 284.31 g · mol-1
Mgbu Point 125-126ºC (dec.)
esi ebe 498.6 ± 45.0 Celsius C na 760 mmHg
Ọkara Ndụ nke Ndụ Enweghị Data Dị
Agba nchapụ ọcha
Sume Soluble na ethyl acetate na 50mg / ml. Soluble na DMSO na ethanol.
Sịkwa akwa Tigwe Chekwaa na 0 Celsius C
Raw Caffeic acid phenethyl ester ntụ ntụ Antinye Onye na-agwọ ọrịa cytotoxic megide mkpụrụ ndụ cancer. Onye na-emechi ornithine decarboxylase na protein tyrosine kinase. Achọpụtara na ọ bụ onye na-emechi ihe na-emepụta ihe nuklia, NF-kB. E gosipụtakwala na ọ ga-eme ka ụzọ lipoxygenase daba nke ọma nke arachidonic acid metabolism n'oge mbufụt.

Raw Caffeic acid phenethyl ester powder (104594-70-9) Nkọwa

Raw Caffeic acid phenethyl ester powder bụ phenethyl alcoholic ester nke caffeic acid na ihe na-emepụta ihe na-emepụta mmanụ aṅụ nke anụ ọhịa na-ekpo ọkụ, nke nwere antineoplastic, cytoprotective na mmekorita ọrụ. N'elu nlekọta, Raw Caffeic acid phenethyl ester powder (CAPE) na-egbochi ịmepụta ihe kpatara nsụgharị nuklia NF-kappa B ma nwee ike ibelata ụzọ p70S6K na okporo ụzọ mgbaàmà Akt. Tụkwasị na nke ahụ, CAPE na - egbochi ntinye ụbụrụ nke PDCF - nke na - eme ka mkpụrụ ndụ dị nro na - eme nke ọma na - arụ ọrụ site na ntinye nke protein P38 na - eme ka protein kinase (MAPK) na ihe hypoxia-inducible (HIF) -1alpha na ụmịnye nke heme oxygenase-1 (HO-1) .

A kọwo Caffeic acid phenethyl ester nwere mgbochi carcinogenic, mgbochi mkpali, na ụdị immunomodulatory. CAPE na-egbochi nje HIV-1. Echere na a na-echepụta àgwà ndị na-egbu egbu na-egbu egbu site na nkwụsị nke ụzọ lipoxygenase nke CAPE arachidonic acid metabolism. Nnyocha a gosipụtakwala CAPE ka ọ bụrụ onye na-egbochi ya ịmepụta ihe ntụgharị nke nuklia NF kappa B, nke bụ protein nke na-achịkwa transcription nke DNA. Caffeic Acid Phenethylester bụ onye na-emechi ODC na Tyrosine Kinase

Caffeic acid phenethyl ester ntụ ntụ (104594-70-9) Mechanism of Action

Caffeic acid phenethyl ester bụ ihe mejupụtara nke propolis nke ndị na-ahụ maka mmanụ aṅụ, ọ na-egbochi NF-κB mmezi sitere na phorbol ester, ceramide, okadaic acid, na hydrogen peroxide site na igbochi ntụgharị nke p65 nke NF-κB. N'ihe dị iche iche nke usoro ọgwụ, Caffeic acid phenethyl ester na-egosi ọrụ mmegide na EC50 nke 1.76, 3.16, 13.7, na 44.0 μM megide colonel 26-L5, nje B16-BL6 melanoma, HT-1080 fibrosarcoma mmadụ na A549 anụ ọkụ mmadụ. adenocarcinoma cell lines, kwa. Caffeic acid phenethyl ester, dị ka antioxidant nwere ike, na-arụ ọrụ mgbochi apoptotic na mkpụrụ ndụ mkpụrụ ndụ ọka ụbụrụ site na igbochi nhazi nke ROS ma gbochie ọrụ nchụpụ. Ọzọkwa, Caffeic acid phenethyl ester na-emepụta pro-inflammatory phenotype nke LPS-kpaliri HSCs, na LPS na-emetụta nke sensitization nke HSCs ka cycokines fibrogenic site na-egbochi NF-κB akara.

Na vidio, Caffeic acid phenethyl ester (10 mg / kg, ip) na - egbochi uto na angiogenesis nke ụbụrụ isi na C57BL / 6 na BALB / c ụmụ ụgbụ ejiri Lewis lung carcinoma, coloncin carcinoma, na sel melanoma. Caffeic acid phenethyl ester (5, 10, 20 mg / kg) na-egosipụtakwa mmetụta immunomodulatory na vivo site na-ebelata thymus arọ na / ma ọ bụ cellularity nke thymus na splin.

Iji Caffeic acid acid phenethyl ester (104594-70-9)

▪ Ọkpụkpụ na-egbuke egbuke

▪ Aantiinflammatory

▪ Onye na-enye gị nsogbu

▪ NFkB blocker

uru nke Caffeic acid phenethyl ester ntụ ntụ (104594-70-9)

Pentethyl caffeate bụ onyinye dị na propolis, ngwakọta nke aṅụ na-emepụta. Caffeic acid phenethyl ester (CAPE) nwere ike ịdị irè n'igbochi na ịgwọ ọrịa ọrịa ndị na-egbu egbu gụnyere ọrịa arthritis rheumatoid, systemic lupus erythematosus na psoriasis, ọrịa na ọrịa ndị dịgasị iche iche gụnyere ọgwụ e guzobere, cataracts, na ọrịa ndị ọzọ na - akpata nrụgide oxidative. Ọzọkwa, a pụrụ iji CAPE mee ihe banyere ọrịa HIV mgbe ejikọtara ya na ihe na-emepụta ọgwụ na ihe na-egbochi njegharị nje HIV. A pụkwara iji ya mee ihe na-emegide atherosclerotic, antioxidative, cardioprotective, mgbochi oké ibu na antimitogenic.

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