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Ngwakọta Ngwakọta Nicotinamide Mononucleotide (NMN) (1094-61-7)

Raw Nicotinamide Mononucleotide (NMN) uzuzu kwusiri uru uzo di n'umu aru ......


ọnọdụ: Na Production Production
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ikike: 1370kg / ọnwa

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Raw Nicotinamide Mononucleotide (NMN) ntụ ntụ (1094-61-7) video

Ngwakọta ntụpọ Nicotinamide Mononucleotide (NMN) (1094-61-7) Nkọwapụta

Raw Nicotinamide Mononucleotide powder ("NMN" na "β-NMN") bu nucleotide nke sitere na ribose na nicotinamide. Dị ka nbotinamide riboside, NMN bụ ihe mgbapụta nke niacin, ụmụ mmadụ nwere enzymes nwere ike iji NMN mee ka nenotinamide adenine dinucleotide (NADH).

N'ihi na NADH bụ onye na-arụ ọrụ maka ime ihe n'ime mitochondria, maka ndị isi, na maka PARP, NMN a mụọla ụdị anụmanụ dịka onye na-ahụ maka na ọ bụ na-egbochi ya. Ndị na-arụ ọrụ na-eri nri na-eri nri na-ere ahịa NMN ngwaahịa ndị na-azọrọ uru ndị ahụ, ọ bụ ezie na ọ dịghị nnyocha ọmụmụ gbasara ụmụ mmadụ bipụtara.

Raw Nicotinamide Mononucleotide (NMN) ntụ ntụ (1094-61-7) Nkọwapụta

Product Name Raw Nicotinamide Mononucleotide (NMN) ntụ ntụ
Chemical Aha Beta-nicotinamide ribose monophosphate; Raw Nicotinamide Mononucleotide ntụ ntụ; AC1Q6RVF; AC1L23AN; NMN (+); SCHEMBL6858129
Brand Name Mirailabo
Klaasị ọgwụ ọjọọ Ntinye nri
CAS Number 1094-61-7
InChIKey DAYLJWODMCOQEW-TURQNECASA-N
molekụla Fnhazi C11H15N2O8P
molekụla Wasatọ 334.22
Nkịtị Monoisotopic 335.229 g / mol
Mgbu Point > 96 Celsius C
Fna-agbanyeghachi Point Ọ dịghị ụbọchị dị
Ọkara Ndụ nke Ndụ Ya mere, dị ka e gosiri na fig 3, nicotinamide kwụsịrị na ọbara na ọkara ndụ nke 5.3 awa, ebe ọkara nke ndụ nicotinic bụ 1.1 hour.
Agba White na-acha ọcha ntụ ntụ
Sume Methanol (Slightly), Mmiri (Obere)
Sịkwa akwa Tigwe Hygroscopic, -20˚C Freezer, N'okpuru Gburugburu Inert
Antinye Iji mee ka ọrụ ndụ dị ogologo na ịgwọ ọrịa shuga

Raw Nicotinamide Mononucleotide (NMN) ntụ ntụ (1094-61-7) Nkọwa

Raw Nicotinamide Mononucleotide powder ("NMN" na "β-NMN") bu nucleotide nke sitere na ribose na nicotinamide. Dị ka nbotinamide riboside, NMN bụ ihe mgbapụta nke niacin, ụmụ mmadụ nwere enzymes nwere ike iji NMN mee ka nenotinamide adenine dinucleotide (NADH).

Nyocha ọhụrụ na-enye echiche na NMN nwere ike weghachite metabolism cell, ma nwee mmetụta dị oke nká. Na-emekarị ahụ, NMN (β-Nicotinamide mononucleotide) dị oké mkpa maka ntụgharị nke nri na ike. Ịtinye NMN dị ka akụkụ nke usoro nchịkwa gị kwa ụbọchị nwere ike inye umeghachi ume, nchebe site na ịka nká, ma belata nsogbu nke nsogbu obi. NMN bụ cofactor na mmeghachi omume ndị ọzọ, usoro dị oke egwu maka ọrụ metabolic n'iwepụta ATP nke mgbagwurugwu dị elu. NMN nwere onyinye ọrụ ncheta nke na-akwalite nkwekọrịta metabolic na ogologo oge.

Iji Nicotinamide Mononucleotide (NMN) ntụ ntụ (1094-61-7)

  1. Ngwurugwu Nicotinamide mononucleotide na mkpụrụ ndụ mmadụ na-arụ ọrụ dị mkpa n'inwe ike, ọ gụnyere NAD intracellular (nicotinamide adenine dinucleotide, mkpanaka ume ume dị mkpa coenzyme) njikọ, eji mee ihe na mgbochi nká, ịdaba ọbara na ọgwụ ndị ọzọ.
  2. Nicotinamide Mononucleotide bụ vitamin soluble mmiri, Ngwaahịa ahụ bụ white crystalline ntụ ntụ, odorless ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ odorless, na-atọ ụtọ na uto, na-enweghị soluble na mmiri ma ọ bụ ethanol, dissolvable na glycerin.
  3. Nicotinamide Mononucleotidepowderis dị mfe ịmịnye ọnụ, ma nwee ike kesaa ya na ahụ, ihe mgbochi ma ọ bụ prototype na-apụ ngwa ngwa site na mmamịrị. Nicotinamide bụ akụkụ nke coenzyme m na coenzyme nke Abụọ na-arụ ọrụ nke nnyefe ọbara na usoro ọgwụgwọ oxyidation nke ndụ, nwere ike ịkwalite usoro ọgwụgwọ oxidation na anụ ahụ metabolism, ịnọgide na-enwe anụ ahụ nkịtị (karịsịa akpụkpọ anụ, tractestive tract na ụjọ ụjọ) iguzosi ike n'ezi ihe nwere ọrụ dị mkpa.

Tụkwasị na nke a, nicotinamide nwere mgbochi na ngwọta nke ngọngọ obi, ọrụ nhicha mmehie na mgbochi ngwa ngwa nke arrhythmias, nicotinamide nwere ike ime ka obi dịkwuo elu ma ọ bụ mgbanaka nke na-eme ka verapamil kpatara ya.

uru nke Nicotinamide Mononucleotide (NMN) ntụ ntụ (1094-61-7)

  • NMN Na - eme Ka Ike Metabolism - NAD + na - enyere aka ịkwụsị nri dị ka sugars n'ime ike.
  • Na-akwalite Brain Nwere Ahụ Ike na Ọrụ Obi.
  • Imechi Ndaghachi DNA - A na - eji NAD + rụọ eriri DNA gbaruru.
  • SIRTUIN Activator - NAD + chọrọ maka mkpụrụ ndụ ogologo ndụ anyị ka anyị rụọ ọrụ.
  • NMN bụ Nchịkọta nke ndị ọkà mmụta sayensị Harvard ji mee ihe iji weghachite ụfọdụ ihe ịrịba ama nke anụ ahụ meworo agadi na ụmụ oke ndị malitere ọsọsọ na NAD.
  • NMN ọgwụgwọ na-echebe megide cICH-induced nnukwu ụbụrụ mmerụ
  • NMN Ọgwụgwọ na-anapụ ihe mgbochi ime
  • Nicotinamide mononucleotide na-egbochi JNK ịmegharị ka ọ gbanwee ọrịa Alzheimer
  • NMN nwere ike iweghachi cognition na eriri nlereanya AD

Na-atụ aro Nicotinamide Mononucleotide (NMN) ntụ ntụ (1094-61-7) Ọgwụgwọ

Ngwá ọgwụ a na-atụkarị aro maka Ngwakọta Nicotinamide Mononucleotide bụ ebe ọ bụla n'etiti 250 - 1500 mg kwa ụbọchị.

NMN na-etinye uche ngwa ngwa ngwa ngwa ma nwee obere ndụ, ya mere iji mee ka NAD + dị elu karịa ụbọchị ọ bụla o kwere mee, a na-atụ aro ka ị were otu capụle 125 mg na edemede na ọzọ n'ehihie ma ọ bụrụ na ị na-ewere 250 mg kwa ụbọchị.

mmetụta nke Nicotinamide Mononucleotide (NMN) ntụ ntụ (1094-61-7)

Ọ bụ ezie na Nicotinamide mononucleotide (NMN) bụ ntụsị ọhụrụ ọhụrụ na nchọpụta na-aga n'ihu, nnyocha e mere na-egosi ugbu a na ọ dị mma ma bụrụ nke na-adịghị egbu egbu.

Mmetụta dị iche iche na-adịkarị ụkọ, ma ọ dị nro, dizziness, sweating, na ọgbụgbọ na-akọ na ụfọdụ.


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Ntughari & akwukwo akwukwo

2019 Mgbochi Ọgwụ Ndị Na - emegide Mgbochi: Nicotinamide Mononucleotide (NMN)

References

  1. Mills, KF, Yoshino, J., Yoshida, S., et al. (2016). Njikwa Ogologo oge nke Nicotinamide Mononucleotide Mitigates Age Physicallogical Decline in Mice. Cell Metabolism.
  2. Yoshino, J., Mills, KF, Imai, SI, na Yoon, MJ (2011). Nicotinamide Mononucleotide, isi NAD + Intermediate, Na-emeso Pathophysiology nke Ọgwụ Nri - na Ọrịa Na-arịa Ọgbọ na Ụmụaka. Cell Metabolism.
  3. Yamamoto, T., Byun, J., Zhai P., Ikeda, Y., Oka, S., na Sadoshima, J. (2014). Nicotinamide Mononucleotide, Nkeji nke NAD, na-echebe Obi si Ischemia na Reperfusion.
  4. Sinclair, DA, Uddin, GM, Youngson, NA, na Morris, MJ (2016). Na-ejiri NAD + kọọkọ Nicotinamide Mononucleotide (NMN) na izu isii nke mmega na Obese Ụmụ nwanyị.
  5. Imai, S., Yoshino, J., Mills, KF, Grozio, A., et al. (2019) Slc12a8 bụ Nicotinamide Mononucleotide Transporter. Nature Metabolism.
  6. De Picciotto, NE, Mills, KF, Imai, S., Gano, LB, et al. (2016). Nicotinamide Mononucleotide Na-agbanwe Ọkpụkpụ Na-ahụ Maka Ọkpụkpụ na Ahụhụ Na-akpata Oxidative na Mice Aging.
  7. Yao, Z., Gao, Z., Yang, W., na Jia, P. (2017). Nicotinamide Mononucleotide Inhibits JNK Activation to Reverse Alzheimer Disease.
  8. Hou, Y., Wang, Y., Zhang, Y., Lautrup, S., et al. (2018). NAD + Mgbakwunye Na-eme ka atụmatụ Alzheimer dị elu na DNA Damage Responses in a New AD Mouse Model with Introduced DNA Repair Efficiency.

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