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MT2 (Melanotan-II) ntụ ntụ (121062-08-6)

MT2 (Melanotan-II) uzuzu bụ heptapeptide cyclic synthetic, ihe analog nke alpha-melanotropin (4,10); ike nke .........


ọnọdụ: Na Production Production
Ekekọrịta na ahaziri
ikike: 1277kg / ọnwa

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MT2 (Melanotan-II) ntụ ntụ (121062-08-6) video

MT2 (Melanotan-II) ntụ ntụ (121062-08-6) Nkọwapụta

Melanotan II (MT-2) bụ peptide sịntetik, analogue nke homonụ sitere n'okike na-eme ka melanocortin tan mepụta (melanin site na melanocytes, nke na-ekpebi ma na-eme ka tan), si otú a belata ihe ize ndụ nke mmebi anyanwụ na ndị ọzọ mmetụta ọjọọ nke radieshon na solarium.

Ezubere nke a peptide MT-2 bu iji wee kpalie mmeghachi ahụ nke anụ ahụ maka mkpughe UV ray, n'ihi na mmepụta melanin bụ nke kachasị ekpughere ọhụụ anyanwụ iji nweta nsonaazụ kachasị mma. Nke a bụ ezigbo ihe ngwọta nye ndị nwere akpụkpọ ahụ dị mma ka a na-agba mmiri na-enweghị izu ọwụwa anyanwụ ma na-aga n'ihu n'ọkụ na-agwọ.

Ndị ọrụ MT2 na-enweta ngwa ngwa ngwa ngwa ngwa ngwa ma na-agwọ ngwa ngwa nke sel anụ ahụ mebiri emebi. N'ihi nke a, melanotan II dabara adaba nke ọma na ndị nwere akpụkpọ ahụ na-acha odo odo (ụdị 1 & 2) ma na-enwekarị ọkụ na anyanwụ.

Banyere usoro ọgwụgwọ nke Melanotan II , usoro nnabata ọkọlọtọ na-egosi ị takingụ otu ọgwụ ntụtụ Melanotan II na ọnụego 1 mg (a chọghị ọnụ ọgụgụ kwa kilogram, dị ka usoro onyonyo si dị iche), bido na 250mkg otu ụbọchị na n'ime ụbọchị 4 gbakwunye 250mkg ọzọ nwayọ. N'ụbọchị nke anọ, mee ka ọgwụ ahụ dị elu ruo 1mg ma rapara n ’ọkwa a ruo mgbe a ga-enweta tan chọrọ. Nkọwa ndị ọzọ gbasara ịzụta Melanotan II (MT-2) na ntanetị, biko egbula oge ịgwa anyị onye na - enye ndị ahịa ahịa - peptide.

MT2 (Melanotan-II) ntụ ntụ (121062-08-6) Smmezi

Product Name MT2 (Melanotan-II)
Chemical Aha Melanotan II; MelanotanII;

(3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((S)-2-acetamidohexanamido)-9-benzyl-6-(3-guanidinopropyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide

usoro Ac-Nle-cyclo (Asp-His-DPhe-Arg-Trp-Lys) -NH2
Brand Name N / A
Klaasị ọgwụ ọjọọ peptide
CAS Number 121062-08-6
InChIKey JDKLPDJLXHXHNV-MFVUMRCOSA-N
molekụla Fnhazi C50H69N15O9
molekụla Wasatọ 1024.198 g / mol
Nkịtị Monoisotopic 1023.54 g / mol
Mgbu Point > 181 Celsius C (subl.)
Fna-agbanyeghachi Point ≥17.0
Ọkara Ndụ nke Ndụ 33 hour
Agba White
Sume Soluble na DMSO
Sịkwa akwa Tigwe -20 ° C
Antinye A na-eji nnu acetate nke Melanotan II mee ihe iji mụọ ihe ndị na-emechibido ihe oriri na ume ike na oke.

Melanotan II Acetic Acid Nnu, bụ ọgwụ e ji arụ ọrụ na-emepụta nke yiri nke hormone dị na ndị mmadụ. Melanotan II e gosipụtara melanogenesis (tanning) na mmetụta aphrodisiac na ụmụ mmadụ.


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COA

foto COA 121062-08-6 Melanotan-II Phcoker_zpscxfonz6w.jpg

Ntughari & akwukwo akwukwo

Ihe Nkọwa 6 na Melanotan-II / MT2 nke ị chọrọ ịma

References

  1. Wessells, H., Levine, N., Hadley, ME, Dorr, R., & Hruby, V. (2000). Melanocortin agonists, penile erection, na akpali agụụ mmekọahụ: ọmụmụ ụmụ mmadụ na Melanotan II. Akwụkwọ akụkọ ụwa nke nchọpụta adịghị mma, 12(S4), S74.
  2. Evans-Brown, M., Dawson, RT, Chandler, M., & McVeigh, J. (2009). Iji melanotan I na II n'ime ndị mmadụ niile.
  3. Nelson, ME, Bryant, SM, & Aks, SE (2012). Melanotan II ọgwụ nke na-akpata ọgwụ na-egbu egbu na rhabdomyolysis. Clinical Toxicology, 50(10), 1169-1173.
  4. Heijboer, AC, Van Den Hoek, AM, Pijl, H., Voshol, PJ, Dokes, LM, Romijn, JA, & Corssmit, EP (2005). Nchịkọta nke na-eme ka mpi nke melanotan II na-eme ka insulin nwee mmetụta nke mkpofu glucose na ụmụ oke. Diabetologia, 48(8), 1621-1626.
  5. Breindahl, T., Evans-Brown, M., Hindersson, P., McVeigh, J., Bellis, M., Stensballe, A., & Kimergård, A. (2015). Nyocha na njirimara site na LC-UV-MS / MS nke melanotan II anụ akpụkpọ anụ na-ere na-akwadoghị na Ịntanetị. Ọgwụ nyocha na nyocha, 7(2), 164-172.
  6. Li, G., Zhang, Y., Wilsey, JT, & Scarpace, PJ (2004). Nkpọrọgwụ na-eme ka melanotan II na-eme ihe na-adịghị mma ma na-enwekwu mmelite nke na-eme nri na-edozi ya n'agbanyeghị na mkpụrụedemede ntinye 3 na 4 melanocortin melanocortin. Akwụkwọ nke Endocrinology, 182(1), 123-132.

Shangke Chemical bụ ụlọ ọrụ ọgbara ọhụrụ nke na-ahụ maka ndị na-ahụ maka ọgwụ na-arụ ọrụ (APIs). Iji chịkwaa àgwà n'oge mmepụta, ọnụ ọgụgụ buru ibu nke ndị ọkachamara nwere ahụmahụ, ngwá ọrụ mmepụta mbụ na ụlọ nyocha bụ isi ihe.

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