NKE 2Na (606-68-8)

March 15, 2020

NADH bụ ụdị nicotinamide adenine dinucleotide (NAD) enzyme, ụdị coenzyme na-arụ ọrụ nke onyinye na vitamin B3 ……….

 


ọnọdụ: Na Production Production
Ekekọrịta na ahaziri
ikike: 1277kg / ọnwa

NADH 2Na (606-68-8) vidiyo

Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)

Product Name Beta-Nicotinamide adenine dyncleotide disodium nnu (NADH 2Na)
Chemical Aha NADH (nnu nke disodium); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium Nnu; Nicotinamide adenine dinucleotide, belatara;
CAS Number 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L
Obere C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
molekụla Formula C21H27N7Na2O14P2
molekụla arọ 709.4
Nkịtị Monoisotopic 709.088661 g / mol
Melting Point 140-142 ℃
Agba Yellow
Soke iwe 2-8 ℃
Solubility H2O: 50 mg / mL, doro anya na ihe doro anya, edo edo
ngwa Ọgwụ; nri na nri nri;

 

Gini bu Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)?

NADH bụ ụdị nicotinamide adenine dinucleotide (NAD) enzyme, ụdị coenzyme na-arụ ọrụ nke onyinye na vitamin B3. NADH (b-Nicotinamide adenine dinucleotide) Disodium Nnu, belata, makwaara dị ka Nicotinamide adenine dinucleotide, bụ coenzyme na mmeghachi omume redox. Ọrụ ya dị ka onye na-enye onyinye eletrọn na usoro catabolic gụnyere glycolysis, β-oxidation na okirikiri citric acid (Krebs okirikiri, TCA okirikiri). NADH benedium nnu na-esonye na ihe ngosi nke sel, dịka ọmụmaatụ maka mkpụrụ maka poly (ADP-ribose) polymerases (PARPs) n'oge mmebi mmebi DNA. Dị ka nnu nnu nke NADH, a na-eji ya na nri na mgbakwunye nri na ọgwụgwọ ọrịa Parkinson, ọrịa ike ọgwụgwụ na-adịghị ala ala, ọrịa Alzheimer na ọrịa obi.

 

Beta-Nicotinamide adenine dyncleotide disodium nnu (NADH 2Na) bara uru

Dika coenzyme nke oxidoreductases, NADH benedium nnu bu ihe di nkpa n’ime ka ike nke aru.

- NADH nke na-enweghị nnu na nnu nwere ike ibute nghọta doro anya nke ọma, ịmụrụ anya, itinye uche na ncheta O nwere ike ime ka ụbụrụ gị ghara ịdị nkọ ma nwee ike ime ka ọnọdụ gị dịkwuo elu. Ọ nwere ike ịbawanye ogo ike na ahụ ma melite metabolism, ike ụbụrụ na ntachi obi.

- Nyere ndị nwere nsogbu ịda mba, ọbara mgbali elu ma ọ bụ cholesterol dị elu;

- Meziwanye arụmọrụ egwuregwu;

- Ghichaa usoro ịka nká ma jigide iguzosi ike n'ezi ihe nke mkpụrụ ndụ akwara iji kwado usoro ụjọ ahụ;

- Nwere ike ịgwọ ọrịa Parkinson, melite ọrụ nke ndị na-ahụ maka ntanetị na ụbụrụ nke ndị ọrịa nwere ọrịa Parkinson, belata nkwarụ anụ ahụ na mkpa ọgwụ;

- Agwọ ọrịa na-adịghị ala ala (CFS), ọrịa Alzheimer na ọrịa obi;

- Chebe onwe gị pụọ na nsonaazụ nke ọgwụ ọgwụ akpọrọ zidovudine (AZT);

- Guzogide ihe ọ alcoholụ onụ mmanya na-aba n’anya n’imeju;

- Jet lag

 

Beta-Nicotinamide adenine dyncleotide disodium nnu (NADH 2Na) mmetụta:

Ka ọ dị ugbu a, nnu diskium NADH yiri ka ọ nweghị ihe ọ bụla maka ya mgbe ejiri ya n'ụzọ dị mma na obere oge, ruo izu iri na abụọ. Otutu ndi mmadu anaghi enwe nsogbu o bula mgbe ha na ewere ego a tụrụ aro kwa ubochi, nke bu 12 mg.

Agbanyeghị, enweghi data zuru ezu banyere iji NADH nnu nnu mee n'oge afọ ime na inye nwa ara, yabụ, ha kwesịrị ịnọ n'akụkụ echekwa ma zere iji ya.

 

Ntughari:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - usoro ọgwụgwọ ọhụrụ maka ọrịa Parkinson. Tụnyere nke ngwa na nke nne na nna. Ọrụ Neurol Scand Suppl 1993; 146: 32-5.
  • Budavari S, ed. Ndepụta nke Merck. Nke iri na abụọ ed. Houselọ Whitehouse, NJ: Merck & Co., Inc., 12.
  • Bushehri N, Jarrell ST, Lieberman S, et al. O na -eme ka ọnụnọ B-nicotinamide adenine dinucleotide (NADH) na-emetụta ọbara mgbali, pepaxidation lipid, na profaịlụ egbugbere ọnụ na oke oke ọbara (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. O na -eme ka ọnụnọ B-nicotinamide adenine dinucleotide (NADH) na-emetụta ọbara mgbali, pepaxidation lipid, na profaịlụ egbugbere ọnụ na oke oke ọbara (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Oen coenzyme Q10 na mgbakwunye NADH na-eme ka ike gwụ ya na usoro biochemical na syndrome na-adịghị ala ala? Ihe akara Antioxid Redox 2015; 22 (8): 679-85.
  • Dizdar N, Kagedal B, Lindvall B. Ọgwụgwọ ọrịa Parkinson na NADH. Ọrụ Neurol Scand 1994; 90: 345-7.