Nicotinamide riboside chloride (NR-CL) (23111-00-4) Ọgwụ

March 11, 2020

Nicotinamide riboside (NR) bụ ihe ọhụrụ achọpụtara vitamin nicotinamide adenine dinucleotide (NAD +). Ihe …….

 


ọnọdụ: Na Production Production
Otu: 25kg / Drum

 

Nicotinamide riboside chloride (NR-CL) (23111-00-4) vidiyo

Nicotinamide riboside chloride (NR-CL) (23111-00-4) Smmezi

Product Name Nicotinamide riboside chloride (NR-CL) (23111-00-4) Ọgwụ
Chemical Aha NRC; 3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride; Nicotinamide ribose chloride; 3-Carbamoyl-1- (β-D-ribofuranosyl) pyridinium chloride; 3-carbamoyl-1 - ((2R, 3R, 4S, 5R) -3,4-dihydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyridin-1-ium chloride; Nicotinamide BD Riboside Chloride (WX900111); NR-CL;
CAS Number 23111-00-4
InChIKey YABIFCKURFRPPO-IVOJBTPCSA-N
Obere C1 = CC (= C [N +] (= C1) C2C (C (C (O2) CO) O) O) C (= O) N. [Cl-]
molekụla Formula C11H15ClN2O5
molekụla arọ 290.7002
Nkịtị Monoisotopic 290.066949 g / mol
Melting Point N / A
Agba acha ọcha
Soke iwe -20 Celsius C Freezer
ngwa nri mmeju, ubi ogwu

 

Gịnị bụ Nicotinamide riboside chloride(NR-CL)?

Nicotinamide riboside (NR) bụ vitamin nicotinamide ọhụrụ adenine dinucleotide (NAD +) achọpụtara. Isdị kristal nke NR chloride ka akpọrọ NIAGEN, nke bụ n'ụdị nicotinamide riboside na isi iyi nke nicotinamide n'ụdị nicotinic acid nwere ike ịbụ nke a na-ahụkarị na ọ bụ nchekwa (GRAS). NR chloride bụ isiokwu nke ihe mmụta nri ọhụrụ abụọ, nke a na-ejikarị nri nri.

Nicotinamide Riboside Chloride bụ ihe na-emepụta ihe dị na mmiri ara ehi. Ọ bụ n'ezie metụtara niacin na ụdị ndị ọzọ nke vitamin B3. Nnyocha ụfọdụ achọpụtawo na Nicotinamide Riboside Chloride nwere ụfọdụ njirimara pụrụ iche nke nwere ike ịkwalite metabolism nke mmadụ iji nyere aka belata calorie ma gbochie uru bara ụba. Na mgbakwunye na ọnwụ ọnwụ, ọ na - enye aka ịkwalite arụmọrụ ahụ, bulie mmefu ike, ma belata ihe egwu nke ọrịa shuga.

Ọzọkwa, nyocha n'ime ụmụ mmadụ egosila na ma Nicotinamide Riboside Chloride welitere ọkwa NAD +, nke na-enyere aka ịkwụsị ọnọdụ ụfọdụ metụtara afọ, ọ bụ ezie na ọ ga-amata na ọ ga-adịte aka.

 

uru nke Nicotinamide riboside chloride(NR-CL)

Nicotinamide riboside chloride bụ ihe sịntetik nke nicotinamide riboside, uru ya / ọrụ ya dị ka nicotinamide riboside. Ọ na-ekere òkè na metabolism n'ime ahụ, enwere ike iji gbochie pellagra ma ọ bụ ọrịa mgbapụ ọrịa niacin na iji belata cholesterol na triglycerides n'ime ọbara. A na-ejikwa ya iji belata ihe ize ndụ nke nkụchi obi na ndị nwere cholesterol dị elu ndị nweburu nkụchi obi. Mgbe ụfọdụ a na-eji ya agwọ ọrịa akwara ọbara (atherosclerosis), kpuchido chebe ụbụrụ na imeju (obi, ọrịa shuga, ọrịa Alzheimer).

Na mgbakwunye, Nicotinamide riboside chloride nwekwara abamuru ndị ọzọ na mmadụ:

  • Mgbaze nke ọma na ịmịkọrọ protein na abụba;
  • Nyere aka gbanwee amino acid tryptophan n’ime niacin;
  • Belata voming, belata nsonaazụ nke ị antụ ọgwụ mgbochi n'ihi ọnya kpọrọ nkụ na urin urin nke ike;
  • Kwalite njikọ nke nucleic acid ma gbochie ịka nká nke anụ ahụ na akụkụ ahụ, si otú ahụ mezuo ebumnuche nke igbu oge;
  • Ọkpụkpụ mọzụlụ na-adị nwayọ, ọrịa mkparị spastic na aka na ukwu neuritis;
  • Ọgwụ hypometabolism ịmụ nwa na nkwalite metabolism;
  • Mgbochi na ọgwụgwọ nke ụkọ vitamin B6;
  • Ọgwụgwọ carpal ọwara syndrome;
  • Na-enyere aka felata ma na-ewusi ọrụ ike.
  • Mee ka ahụ mmadụ ghara ịda mbà na mkpụrụ ndụ kansa
  • Na-egbochi ịnụ ntị
  • Ọ bụ okike ọdịrịkpa.
  • Iwere oke ogwu nwere ike belata iri riri ahu ma nwee ezigbo nsacha.
  • Meziwanye ọrụ nke mkpụrụ ndụ epidermal, yana ọrụ nke mkpụrụ ndụ ndị ọzọ na ahụ mmadụ, iji mee ka akpụkpọ ahụ na-egbuke egbuke.

 

Nicotinamide riboside chloride(NR-CL) iji

N'ihi Nicotinamide riboside chloride nwere ezigbo ọgwụ ọgwụ, a na-ejikarị ya na mgbakwunye nri, ọgwụ na ubi nri.

 

 

Ntughari:

  • Conze D, Brenner C, Kruger CL. Nchekwa na Nchịkwa nke Metụtara ogologo oge nke NIAGEN (Nicotinamide Riboside Chloride) na Randomized, okpukpu abụọ, kpuru ìsì na ọnwụnwa nke Clinical Healthy Overweight. Sci Rep. 2019 Jul 5; 9 (1): 9772. doi: 10.1038 / s41598-019-46120-z. PMID: 31278280 PMCID: PMC6611812.
  • Bogan, KL, Brenner, C. (2008). "Nicotinic acid, nicotinamide, na nicotinamide riboside: nyocha nyocha nke molekụla nke NAD + vitamin na-edozi ahụ na nri mmadụ". Annu. Rev. Nutr. 28: 115-130. ma ọ bụ: 10.1146 / annurev.nutr.28.061807.155443. PMID 18429699.
  • Chi Y, Sauve AA (Nọvemba 2013). "Nicotinamide riboside, ihe na-edozi ahụ na nri, bụ vitamin B3 nwere mmetụta na metabolism metabolism na neuroprotection". Curr Opin Clin Nutr Nlekọta. 16 (6): 657–61. ma ọ bụ: 10.1097 / MCO.0b013e32836510c0. PMID 24071780.