Dihydromyricetin (DHM) (27200-12-0)

March 9, 2020

Dihydromyricetin (ma ọ bụ DHM) bụ ihe ewepụtara na Osisi Raisin Japanese nke ejirila ọtụtụ narị afọ dịka mgbochi mmanya …….


ọnọdụ: Na Production Production
Ekekọrịta na ahaziri
ikike: 1277kg / ọnwa

Dihydromyricetin (DHM) (27200-12-0) vidiyo

Dihydromyricetin Smmezi

Product Name Dihydromyricetin (DHM)
Chemical Aha Ampelopsin
Ampeloptin
(+) - Dihydromyricetin
ika aha N / A
Klaasị ọgwụ ọjọọ phytochemical; ụkpụrụ ntụpọ sitere na ọgwụ ọgwụ na Chinese (TCM); mwepụta ahịhịa herbal; ngwaahịa eke; Inhibitors; Flavanones; ọgwụ kemịkal; na ọgwụ ọgwụ.
CAS Number 27200-12-0
InChIKey KJXSIXMJHKAJOD-LSDHHAIUSA-N
molekụla Fnhazi C15H12O8
molekụla Wasatọ 320.25 g / mol
Nkịtị Monoisotopic 320.053217 g / mol
esi ebe 780.7 ± 60.0 Celsius C (Eburu amụma)
Fna-agbanyeghachi Point N / A
Ọkara Ndụ nke Ndụ N / A
Agba acha ọcha ka beige
Sume DMSO: ≥5mg / mL (ọkụ)
Sịkwa akwa Tigwe <+ 8 Celsius
Antinye 1. etinyere na ụlọ ọrụ nri, ntụ ntụ dihydromyricetin eji dị ka akụrụngwa;
2. etinyere na ngwaahịa ahụike, ntụ ntụ dihydromyricetin eji dị ka akụrụngwa iji kwalite ọgụ anụ ahụ;
3. etinyere na mpaghara ọgwụ, dihydromyricetin wepụ ntụ ntụ eji mee ihe dị ka capsules ma ọ bụ ọgwụ iji gwọọ ọrịa okuku ume ma kpuchido imeju.

Dihydromyricetin Akụkọ

Dihydromyricetin (ma ọ bụ DHM) bụ mmịpụta sitere na Osisi Raisin Japanese nke ejirila na narị afọ dị ka ọgwụ mgbochi mmanya na ọgwụgwọ mmanya na ọgwụ ọdịnala Korea na nke China. Nnyocha ndị e mere n'oge na-adịbeghị anya na-egosi na DHM nwere ike belata ọkwa mmanya mmanya gị ma chebe imeju gị na mmebi na ọrịa.

DHM bụ flavonoid a na-ahụkarị site na Vine Tea mana enwere ike ịdọrọ ya n'ụgbụgbọ osisi Holvenia Dulcis. Ma nke kachasị mkpa, Dihydromyricetin nwere akụkọ ntanetị ogologo oge a na-ewere ya kpọmkwem maka ebumnuche nke ịgwọ isi ọwụwa na hangovers.

Gini bu Dihydromyricetin?

Dihydromyricetin, makwaara dị ka Ampelopsin, bụ flavanonol, ụdị flavonoid. A choputara ya na umu ampelopsis japonica, megalophylla, na grossedentata; Jaercicum nke Cercidiphyllum; Hovenia dulcis; Rhododendron cinnabarinum; ụfọdụ ụdị Pinus; na ụfọdụ ụdị Cedrus, yana Salix sachalinensis.

Dihydromyricetin wepụ ntụ ntụ, isi ihe na - arụ ọrụ bụ flavonoids. Na ọrụ nke na-atụgharị radicals free, antioxidants, antithrombotic, Tumor, anti-inflammatory na mmetụta peculiar ndị ọzọ; Dihydromyricetin bụ kọlụ pụrụ iche flavonoid. Na mgbakwunye na njirimara izugbe nke flavonoids, o nwekwara ike iji belata nsị mmanya, igbochi imeju na-egbu egbu, imeju abụba, na igbochi mkpụrụ ndụ imeju. Na-emebi ma belata ọrịa cancer nke imeju. Ọ bụ ezigbo ngwaahịa maka ichebe imeju na mgbochi mmanya.

Dihydromyricetin uru

ANYANWU ANTI-HANGOVER

Isi uru DHM bụ mgbochi na mbelata nke hangovers, iji chebe imeju na ụbụrụ gị. Nke a na-enweta site na nkwalite nke mmanya dehydrogenase (ADH) na acetaldehyde dehydrogenase (ALDH), bụ ndị bụ isi enzymes na-akpata imebi mmanya na acetaldehyde n'ime ahụ.

Acetaldehyde akpan akpan bụ kemịkalụ na-egbu egbu nke ukwuu yana otu n'ime ihe na-akpata hangovers. Mgbe emeziwanye enzymes ndị a, mmanya na acetaldehyde nwere ike ịkụda ngwa ngwa karịa ka ọ dị na nke nkịtị.

AHA IGBO CELLULAR

DHM nwere ọtụtụ akụrụngwa ahụike cellular na-enyefe onwe ha n'ịkwalite ahụike nke ọgụgụ isi. Nke a na - eme n'ihi DHM na - akwalite heme-oxygenase-1 (HO-1), enzyme nke na - egbochi nrụrụ nke heme ma na - ebute ngwongwo ahụike cellular. Dihydromyricetin nwekwara ike ịkwalite ahụ ike imeju.

Isi uru dihydromyricetin

1) Dihydromyricetin nwere ike ikpochapụ radical na ahụ na antioxidation

2) Dihydromyricetin nwere ike ịlụ ọgụ Antibiotic

3) Dihydromyricetin nwere ike ichebe imeju: Dihydromyricetin nwere ọrụ mgbochi inhibitory dị elu nke ịrị elu nke AlT na AST n'ọbara ọbara. Ọ nwere ike belata ngụkọta ọnwa n'ime ọbara ọbara. Yabụ na o nwere ọrụ siri ike nke wedata aminotransferase na jaundice.

4) Dihydromyricetin nwere ike belata ọkwa shuga na abụba ọbara: Dihydromyricetin nwere ike belata ọkwa abụba ọbara na òké. Ọ nwere ike belata mmebi nke mkpụrụ ndụ imeju nke oke abụba ọbara dị elu ma melite ike antioxidation. N'otu oge, ọ nwere ike belata ọkwa nke shuga dị elu.

5) Dihydromyricetin nwere ike ịlụ ọgụ

6) Dihydromyricetin nwere ike Ndo tumo: Dihydromyricetin ntụ ntụ nwere ike gbochie mkpụrụ ndụ nke mkpụrụ ndụ tumo.

Dihydromyricetin side effects.

N'ozuzu, enwere nanị ọmụmụ ole na ole ruo ugbu a na-elele profaịlụ akụkụ mmetụta DHMs na ruo ugbu a ọ nweghị nsogbu ọjọọ a kọrọ.

Nchọpụta ngwa ngwa na Amazon ga-egosi ọtụtụ puku nyocha. Na-elele ha, enwere akụkọ ụfọdụ nke mkpesa afọ, ọgbụgbọ, na ọnya afọ. Agbanyeghị, enweghị ọtụtụ ndị ahịa na-akọ oke mmetụta ndị a.

Dihydromyricetin na-eji na ngwa

na-eji:

  1. Dihydromyricetin uzuzu eji chekwaa imeju;
  2. Dihydromyricetin ntụ ntụ ejiri mezie abụba ọbara shuga;
  3. Dihydromyricetin ntụ ntụ nwere mmetụta nke ịkwalite ọgụ ahụ;
  4. Dihydromyricetin ntụ ntụ na ọrụ nke antioxidant na mgbochi cancer;
  5. Dihydromyricetin ntụ ntụ ejiri ọgwụ nje mee ihe, na-agwọ ụkwara, mgbu ma wepụ nsí anwụrụ.
  6. Dihydromyricetin nwere atụmanya mmepe mmepe na nhazi nke ngwaahịa nlekọta anụ ma ọ bụ ọgwụ maka igbochi na ịgwọ mmerụ ahụ dị nro.

ngwa

  1. Etinyere na ụlọ ọrụ nri, ntụ ntụ dihydromyricetin eji dị ka akụrụngwa;
  2. Etinyere na ngwaahịa ahụike, ntụ ntụ dihydromyricetin eji dị ka akụrụngwa iji kwalite ọgụ nke anụ ahụ;
  3. Etinyere ya na ọgwụ ọgwụ, mmiri ọgwụ dihydromyricetin wepụtara dị ka capsules ma ọ bụ ọgwụ iji gwọọ ọrịa ọrịa okuku ume ma kpuchido imeju.

Dihydromyricetin research in Ọrịa cancer

N'ezie, enwere ọmarịcha nnyocha na-egosi na dihydromyricetin nwere ike inye aka na ọnọdụ adịghị mma mmanya na-akpọ Hepatocellular carcinoma (HCC). HCC bụ ọnọdụ gosipụtara otu n'ime ọrịa kachasị njọ na oke ọnwụ n'ụwa niile, ma gosipụta ụdị ọrịa kansa kacha ala. Dika DHM gosiputara ikike nchedo na imeju (ya bu oria ogwu) nsonaazụ kpughere na o gbochiri oke ịgbasawanye sel na itinye mgbatị cell na ahịrị sel HCC, na-egosi na DHM bụ onye chọrọ nkwanye ugwu maka ọgwụgwọ nke HCC.

Reference:

Dihydromyricetin na-ebelata akwara doxorubicin na-akpata doxorubicin site na igbochi mbufụt NLRP3 site na mbido SIRT1. Sun Z, Lu W, Lin N, Lin H, Zhang J, Ni T, Meng L, Zhang C, Guo H. Biochem Pharmacol. 2020 Feb 26: 113888. doi: 10.1016 / j.bcp.2020.113888. [Epub n'ihu mbipụta]

Metabolomics nke Mmetụta Nchedo nke Ampelopsis grossedentata na Nnukwu Ọrụ Nchịkọta Dihydromyricetin na imeju nke Fat Diet Hamster. Fan L, Qu X, Yi T, Peng Y, Jiang M, Miao J, Xiao P. Evid based Complement Alternat Med. 2020 Jan 28; 2020: 3472578. doi: 10.1155 / 2020/3472578. eCollection 2020.

Iwu nke ụzọ mgbaàmà nke Ampelopsin (Dihydromyricetin) dị na ọrịa kansa dị iche iche: ịgagharị n'okporo ụzọ na n'okporo ụzọ belata njem. Fayyaz S, Qureshi MZ, Alhewairini SS, Avnioglu S, Attar R, Sabitaliyevich UY, Buha A, Salahuddin H, Adylova A, Tahir F, Pawlak-Adamska E. Cell Mol Biol (Noisy-le-Grand). 2019 Sep 30; 65 (7): 15-20.

Golgi reasilite na stack protein 65 downregulation chọrọ maka mgbochi ọrịa kansa nke dihydromyricetin n'ahụ mkpụrụ ndụ cancer ụmụ nwanyị. Wang F, Chen X, Yuan D, Yi Y, Luo Y.

PLoS Otu. 2019 Nọvemba 26; 14 (11): e0225450. doi: 10.1371 / journal.pone.0225450. eCollection 2019.

NKWUP ANDTA NA NKWU:

A na-ere Ihe Nke A Maka Nchọpụta Naanị. Usoro irere tinye. Ọbụghị maka Oriri mmadu, ma ọ bụ ọgwụ, ọgwụ anụ, ma ọ bụ nke ụlọ.