Urolithin A

April 8, 2021

E gosipụtara Urolithin A iji kpalite mitophagy ma melite ahụike anụ ahụ na ụmụ anụmanụ ochie na ụdị ihe atụ nke ịka nká. Ka ọ dị ugbu a, egosila na ọ gafere ihe mgbochi ụbụrụ ọbara, ma nwee ike ịnwe mmetụta na-adịghị emetụta ọrịa Ọrịa Alzheimer.

Urolithin A (1143-70-0) video

Urolithin A (1143-70-0)nkọwa

Product Name Urolithin A ntụ ntụ
Chemical Aha 3,8-dihydroxy-6H-benzo [c] chromen-6-otu;

3,8-Dihydroxy-6H-dibenzo (b, d) pyran-6-otu;

3,8-Dihydroxyurolithin;

3,8-dihydroxybenzo [c] chromen-6-otu;

6H-Dibenzo [b, d] pyran-6-otu, 3,8-dihydroxy-;

3,8-Hydroxydibenzo-alpha-pyrone;

CAS Number 1143-70-0
InChIKey RIUPLDUFZCXCHM-UHFFFAOYSA-N
SMILES C1=CC2=C(C=C1O)C(=O)OC3=C2C=CC(=C3)O
molekụla Fnhazi C13H8O4
molekụla Wasatọ 228.2 g / mol
Nkịtị Monoisotopic 228.042259 g / mol
agbaze ebe 340-345 ° C
esi ebe  527.9 ± 43.0 Celsius C (Eburu amụma)
Ebe mgbari 214.2ºC
Ọkara Ndụ nke Ndụ Urolithin A dị na mmamịrị ruo elekere 48 mgbe ị juiceụ ihe ọ juiceụ pụ pọmigranet.
Agba White na-agba aja aja
Sume  DMSO: 20 mg / mL, doro anya
Sịkwa akwa Tigwe  2-8 ° C
Antinye Ejiri dị ka mgbakwunye nri na ngwaahịa na-egbochi ịka nká, enwere ike iji belata mbufụt ma lụso kansa ọgụ;

 

Ntughari:

[1] Garcia-Muñoz, Cristina; Ogwu, Fabrice (2014-12-02). "Metabolic Fate nke Ellagitannins: Mmetụta maka Ahụ Ike, na Atụmatụ Nchọpụta Maka Nri Na-arụ Ọrụ Na-agbanwe agbanwe". Nyocha dị oke egwu na Science Food na Nutrition. 54 (12): 1584–1598. ma ọ bụ: 10.1080 / 10408398.2011.644643. ISSN 1040-8398. PMID 24580560. S2CID 5387712.

[2] Ryu, D. et al. Urolithin A na-ebute mitophagy ma na-agbatịkwu afọ na C. elegans ma na-eme ka ahụ ike dị na oke. Nat. Ahụike. 22, 879–888 (2016).

[3] "FDA GRAS mara GRN Nke 791: urolithin A". Nchịkwa nri na ọgwụ ọjọọ na US. 20 Disemba 2018. Weghachite 25 August 2020.

[4] Singh, A .; Andreux, P.; Blanco-Bose, W.; Ryu, D.; Aebischer, P.; Auwerx, J.; Rinsch, C. (2017-07-01). "Urolithin A na-eji ọnụ ekwu okwu dị mma ma na-agbanwezi akwara na mitochondrial biomarkers na ndị agadi". Innovation na nká. 1 (bunye_1): 1223–

[5] Heilman, Jacqueline; Andreux, Pénélope; Tran, Nga; Rinsch, Chris; Blanco-Bose, William (2017). "Nyocha nyocha nke urolithin A, metabolite nke mmadụ microbiota mepụtara na nri nri nke osisi ewepụtara ellagitannins na ellagic acid". Nri nri na Chemical. 108 (Pt A): 289– iche: 10.1016 / j.fct.2017.07.050. PMID 28757461.